Fact Sheet: President Donald J. Trump Unveils the Genesis Missionto Accelerate AI for Scientific Discovery

On November 24, 2025, President Donald J. Trump signed an Executive Order to launch the Genesis Mission, a national initiative aimed at using artificial intelligence to transform scientific research. This initiative assigns the Secretary of Energy the responsibility of coordinating efforts across the country’s laboratories to promote collaboration among researchers, utilize extensive data resources, and leverage advanced computing technologies. The Trump Administration’s goal is to tackle significant scientific challenges while also enhancing national security and economic prosperity.

The Genesis Mission emphasizes the integration of AI into scientific inquiry, responding to concerns about decreasing productivity and research output despite increasing budgets. The program is intended to accelerate advancements in fields such as biotechnology, materials science, and energy production by harnessing AI’s ability to analyze large datasets and perform complex analyses rapidly. The Administration anticipates that this approach will lead to breakthroughs that significantly shorten research timelines, allowing studies that typically take years to be completed in months or even weeks.

In the broader landscape of American AI policy, President Trump has sought to reaffirm the United States’ standing in the field through a series of Executive Orders aimed at promoting AI education and innovation. The AI Action Plan outlines nearly a hundred federal initiatives designed to improve domestic AI infrastructure and encourage international collaborations. Through the Genesis Mission, the Administration is working to foster an environment that promotes partnerships between federal agencies and the private sector, thereby advancing scientific discovery.

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